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Brainwide blood volume reflects opposing neural populations

Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10350-9 Combined functional ultrasound imaging and Neuropixels recording of mouse brains identify two neuronal populations with opposing arousal-related activity and distinct haemodynamic response functions, that occur throughout the brain.

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Brainwide blood volume reflects opposing neural populations